Article
Circulating white blood cells and lung function impairment: the observational studies and Mendelian randomization analysis.
Annals of medicine - 1 Dec 2021
Wu Xiulong, Wang Chenming, Li Hang, Meng Hua, Jie Jiali, Fu Ming, Bai Yansen, Li Guyanan, Wei Wei, Feng Yue, Li Mengying, Guan Xin, He Meian, Zhang Xiaomin, Guo Huan
Abstract excerpt
BACKGROUND: Circulating white blood cell (WBC) counts have been related to lung function impairment, but causal relationship was not established. We aimed to evaluate independent effects and causal relationships of WBC subtypes with lung function. METHODS: The 19,159 participants from NHANES 2011-2012 (n = 3570), coke-oven workers (COW, n = 1762) and Dongfeng-Tongji (DFTJ, n = 13,827) cohorts were included in the...
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