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Article

Causal association between chloride intracellular channel protein 5 and Hashimoto thyroiditis: A Mendelian randomization study.

Medicine - 30 Jan 2026

Zhang Juan, Huang Yingnan, Feng Haibo, Ding Caixia, Yang Yang, Liu Zhigang, Sun Ruifang

Abstract excerpt

This objective was to conduct Mendelian randomization (MR) analysis in order to investigate the potential causal relationship between chloride intracellular channel protein 5 (CLIC5) and Hashimoto thyroiditis (HT). Two separate MR analyses were performed, both using CLIC5 as the exposure variable and HT as the outcome. The first analysis utilized exposure data from genome-wide association study (GWAS) ID:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41630298
DOI: 10.1097/MD.0000000000047347
PMCID: PMC12863814

Genes

CLIC5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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