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Article

Epigenetic and MicroRNA signatures as predictive biomarkers in HCV genotype 4-Induced liver cirrhosis and HCC.

Molecular biology reports - 2 Feb 2026

El-Araby Rady E, Khalifa Mahmoud A, Zoheiry Mona M, Zahran Manal Y, Essawy Faiza M, Rady Mohamed I, Ibrahim Raafat A, El-Talkawy Mohamed D, Gad Alaa

Abstract excerpt

INTRODUCTION: Hepatocellular carcinoma (HCC) and chronic liver disease (CLD) are mostly linked to hepatitis C virus (HCV) infection, especially genotype 4. The advancement of liver cancer is significantly influenced by epigenetic mechanisms, such as DNA methylation and microRNA regulation. AIM OF THE STUDY: This study aimed to assess the expression of two tumor suppressor genes in patients infected with HCV...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to DNA (Cytosine-5-)-Methyltransferase 1

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Source

Identifiers

PMID: 41627584
DOI: 10.1007/s11033-025-11323-3

Genes

DNMT1
CDH1
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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