Article
DNA methylation, microRNAs, and their crosstalk as potential biomarkers in hepatocellular carcinoma.
World journal of gastroenterology - 28 Jun 2014
Anwar Sumadi Lukman, Lehmann Ulrich
Abstract excerpt
Epigenetic alterations have been identified as a major characteristic in human cancers. Advances in the field of epigenetics have contributed significantly in refining our knowledge of molecular mechanisms underlying malignant transformation. DNA methylation and microRNA expression are epigenetic mechanisms that are widely altered in human cancers including hepatocellular carcinoma (HCC), the third leading cause...
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