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X-Ray Repair Cross-Complementing Group 1 Genetic Polymorphisms and the Risk of Sudden Sensorineural Hearing Loss.

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology - 1 Mar 2026

Tai Shu-Yu, Chang Ning-Chia, Hsiao Su-Hui, Chan Leong-Perng, Wu Che-Wei, Wang Ling-Feng, Ho Kuen-Yao, Chien Chen-Yu

Abstract excerpt

OBJECTIVE: Sudden sensorineural hearing loss (SSNHL) is a condition with largely unknown etiology, though both vascular and genetic components have been implicated. The X-ray repair cross-complementing group 1 (XRCC1) gene, involved in DNA repair and oxidative stress response, has been linked to ischemic stroke and noise-induced hearing loss. This study aimed to investigate the association between XRCC1 single...

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Identifiers

PMID: 41622560
DOI: 10.1097/MAO.0000000000004794

Genes

XRCC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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