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Article

Heat shock protein 70 gene polymorphisms in sudden sensorineural hearing loss.

Audiology & neuro-otology - 1 Jan 2012

Chien Chen-Yu, Chang Ning-Chia, Tai Shu-Yu, Wang Ling-Feng, Wu Ming-Tsang, Ho Kuen-Yao

Abstract excerpt

BACKGROUND: Heat shock proteins protect cells and tissues against different types of damage. Previous studies have revealed that the serum level of heat shock protein 70 (HSP70) increases in sudden sensorineural hearing loss (SSNHL) patients. We hypothesized that genetic variants of the HSP70 gene are associated with susceptibility to SSNHL. METHODS: We conducted a case-control study with 160 SSNHL cases and 178...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22922572
DOI: 10.1159/000341815

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