Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Progression of gait dysfunction in incident Parkinson's disease: impact of medication and phenotype.

Movement disorders : official journal of the Movement Disorder Society - 1 Mar 2015

Galna Brook, Lord Sue, Burn David J, Rochester Lynn

Abstract excerpt

Gait impairment in Parkinson's disease (PD) persists despite the use of dopaminergic therapy. Motor phenotype associated with greater postural instability and gait difficulty is related to a greater risk of motor decline and may be influenced by non-dopaminergic pathology. This study documents the progression of gait impairment over 18 months in an incident cohort of PD with regard to phenotype and medication....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cognition Disorders
Share to Disability Evaluation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Dopamine Agents

Share to Gait Disorders, Neurologic

Share to Levodopa

Share to Neuropsychological Tests

Share to Parkinson Disease

Share to Walking

Source

Identifiers

PMID: 25546558
DOI: 10.1002/mds.26110

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Progression of gait dysfunction in incident Parkinson's disease: impact of medication and phenotype.PMID 25546558Read ↗

The Emerging Gait Dysfunction Phenotype in Idiopathic Parkinson’s DiseaseSemantic proximity Read ↗

Exploring spatiotemporal and kinematic gait parameters in individuals with Parkinson's disease across different motor phenotypes: A comparative study with and without dopaminergic therapy.Semantic proximity Read ↗

Parkinson Disease: The Relationship Between Non-motor Symptoms and Motor Phenotype.Semantic proximity Read ↗

Profiles of Motor-cognitive Interference in Parkinson's Disease. The Trail-Walking-Test to Discriminate between Motor PhenotypesSemantic proximity Read ↗

Long-Term Cognitive Decline Related to the Motor Phenotype in Parkinson's Disease.Semantic proximity Read ↗

Association between Parkinson’s Disease subtypes and tests of physical function: the 360-degree turn test is most predictiveSemantic proximity Read ↗

Postural instability/gait disturbance in Parkinson's disease has distinct subtypes: an exploratory analysis.Semantic proximity Read ↗

Cognitive and motor dual task costs reveal distinct gait impairment phenotypes in Parkinson's disease.Semantic proximity Read ↗

The natural history of treated Parkinson's disease in an incident, community based cohort.Semantic proximity Read ↗

Gait Kinematics as Biomarkers of Preclinical Parkinson’s Disease: A Systematic Review of Sensor-Based StudiesSemantic proximity Read ↗

Normal pressure hydrocephalus and cognitive impairment: The gait phenotype matters too.Semantic proximity Read ↗

Phenotype of postural instability/gait difficulty in Parkinson disease: relevance to cognitive impairment and mechanism relating pathological proteins and neurotransmitters.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.