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Mutations in sugar metabolism-related genes driving global drug-resistant Mycobacterium tuberculosis transmission revealed by whole-genome sequencing.

BMC infectious diseases - 30 Jan 2026

Li Yameng, Li Yifan, Kong Xianglong, Tao Ningning, Hou Yawei, Han Qilin, Zhang Yuzhen, Long Fei, Liu Yao, Li Huaichen

Abstract excerpt

BACKGROUND: Tuberculosis (TB) continues to represent a significant global health challenge, particularly due to the emergence of drug-resistant strains that hinder TB control initiatives. Elucidating the mechanisms underlying the proliferation of drug-resistant strains is essential for developing effective strategies to address this public health threat. METHODS: Whole-genome sequencing was conducted on 13,525...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 41618188
DOI: 10.1186/s12879-026-12559-5
PMCID: PMC12930972

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