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Article

Point-of-care profiling of H. pylori virulence and antibiotic resistance from endoscopic biopsies using an integrated restriction enzyme-CRISPR microfluidic platform.

Biosensors & bioelectronics - 1 May 2026

Xu Lei, Jin Jingzheng, Lyu Weiyuan, Liang Xiao, Wang Qi, Zhang Jiajie, Luo Yang, Chen Jinnan, Lu Hong, Li Xiaobo, Shen Feng

Abstract excerpt

Endoscopically obtained gastric mucosal biopsies contain abundant molecular information that could inform Helicobacter pylori (H. pylori) eradication therapy. However, the lack of point-of-care tools for processing solid tissue limits rapid, on-site genotyping, leading to empirical therapy and higher eradication failure rates. Here, we present the SlipChip-based On-site and User-friendly Testing (SCOUT) together...

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PMID: 41616513
DOI: 10.1016/j.bios.2026.118438

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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