Article
A rapid and high-throughput multiplex genetic detection assay for detection, semi-quantification and virulence genotyping of Helicobacter pylori in non-invasive oral samples.
Frontiers in cellular and infection microbiology - 1 Jan 2023
Chi Wenjing, Wang Su, Liu Tao, Jiang Wenrong, Ding Li, Miao Yingxin, Yang Feng, Zhang Jinghao, Ji Danian, Xiao Zili, Zhu Haowei, Wu Yong, Bao Zhijun, Zhao Hu, Wang Shiwen
Abstract excerpt
Aim: This study established a high-throughput multiplex genetic detection assay (HMGA) for rapid identification, semi-quantification and virulence analysis of Helicobacter pylori directly from the clinical non-invasive oral samples. Methods: The gastric mucosa and oral samples were collected from 242 patients in Shanghai from 2021 to 2022. All the samples were detected by routine clinical tests for H. pylori and...
Topics
- Humans
- Helicobacter pylori
- Bacterial Proteins
- Virulence
- Genotype
- RNA, Ribosomal, 16S
- China
- HMGA Proteins
- Helicobacter Infections
- Antigens, Bacterial