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Article

Immunological phenotype as a predictor for response after isolated limb perfusion for patients with melanoma in-transit metastasis.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 Mar 2026

Constantinescu Anna, Olofsson Bagge Roger, Huibers Anne

Abstract excerpt

BACKGROUND: Isolated limb perfusion (ILP) is a regional treatment for patients with melanoma in-transit metastases (ITM) confined to extremities. Reported complete response (CR) rates for ILP varies but is approximately 50-70 %. This study aims to analyze if specific immunological phenotypes could predict CR after ILP. METHODS: 132 patients undergoing ILP as a first treatment for melanoma ITM between January 2012...

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PMID: 41616426
DOI: 10.1016/j.ejso.2026.111424

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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