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Article

Genetic insights into number of long-term conditions and their relationship with lifespan.

PloS one - 1 Jan 2026

Bhak Youngjune, Guthrie Bruce, Tenesa Albert

Abstract excerpt

AIMS: Relationships between the genetic risk for long-term conditions (LTCs) and lifespan have been reported. However, the genetic factors underlying the total number of LTCs an individual has (LTC burden) and their association with lifespan have not been fully investigated. This study aims to investigate the genetics of LTC burden and evaluate its relationship with lifespan. METHODS: A genome-wide association...

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Identifiers

PMID: 41615936
DOI: 10.1371/journal.pone.0340181
PMCID: PMC12857943

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