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Article

HLA-DRB1 Allelic Combinations Differentially Shape Dendritic Cell Antigen Presentation Enhanced by Tumour Cell Line Lysate-Pulsing.

HLA - 1 Feb 2026

Lázaro Gonzalo, Cedano Juan A, Faus Maitane, Roura-Mir Carme, Garrigós Laia, Pérez-García José, Román-García Javier, Cortés Javier, Aran Andrea, Martí Mercè

Abstract excerpt

The anti-tumour immune response plays a pivotal role in eliminating tumour cells, with the presence of tumour-infiltrating lymphocytes (TILs) often correlated with improved patient outcomes. Among these, CD4+ T lymphocytes act as key orchestrators of the immune response, functioning as effector and regulatory cells, and are essential for establishing immunological memory. To better understand the role of CD4+ T...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41607090
DOI: 10.1111/tan.70563
PMCID: PMC12853012

Genes

CD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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