Article
Molecular genetic analysis for the B subgroup revealing two novel alleles in the ABO gene.
Transfusion - 1 Nov 2008
Cai Xiao-Hong, Jin Sha, Liu Xi, Shen Wei, Lu Qiong, Wang Jian-Lian, Fan Liang-Feng, Sun Ji-Li, Liu Da-Zhuang, Xiang Dong
Abstract excerpt
BACKGROUND: B(x) is a very rare ABO blood group phenotype and the molecular mechanism underlying it still remains largely unknown. This study reports two novel B(x) alleles in two Chinese individuals. STUDY DESIGN AND METHODS: Serologic investigations including serum transferase activity assay were performed with standard methods. DNA sequences of all seven exons and exon-intron boundaries of ABO gene were...
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