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Salmonella's lost phenotype: implications of sequence-based serotyping on the characterization of lipopolysaccharide-deficient Salmonella isolates.

Microbiology spectrum - 3 Mar 2026

Wenderlein Jasmin, Stroehlein Andreas J, Pietsch Michael, Simon Sandra, Szabo Istvan, Malorny Burkhard, Lamparter Marina C, Fischer Jennie

Abstract excerpt

Salmonella serotyping is shifting from slide agglutination toward whole-genome sequencing (WGS). While WGS allows for comprehensive analyses, phenotypic information about lipopolysaccharide-deficient ("LPS-rough") isolates obtained from slide agglutination is lost. This discrepancy represents a challenge for Salmonella control in livestock because in the European Union, LPS-rough Salmonella isolated from...

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PMID: 41589840
DOI: 10.1128/spectrum.02498-25
PMCID: PMC12955480

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