Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Malignant neoplasm of skin with risk of sepsis: A bidirectional Mendelian randomization analysis.

Medicine - 23 Jan 2026

Pan Lisha, Hu Jiayu

Abstract excerpt

Sepsis, a life-threatening condition characterized by dysregulated immune responses, shares pathophysiological features with malignant skin neoplasms, including immunosuppression and barrier disruption. Nonetheless, robust evidence for a causal relationship is lacking. To assess the causal association between malignant skin neoplasms and sepsis risk using bidirectional Mendelian randomization (MR). We performed a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Predisposition to Disease
Share to Genome-Wide Association Study
Share to Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Share to Sepsis

Share to Skin Neoplasms

Share to United Kingdom

Source

Open in PubMed Open full text

Identifiers

PMID: 41578565
DOI: 10.1097/MD.0000000000047352
PMCID: PMC12851649

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Malignant neoplasm of skin with risk of sepsis: A bidirectional Mendelian randomization analysis.PMID 41578565Read ↗

Association of cancers with the occurrence and 28-day mortality of sepsis: a mendelian randomization and mediator analysisSemantic proximity Read ↗

Using Mendelian randomization provides genetic insights into potential targets for sepsis treatmentSemantic proximity Read ↗

[Causal association between immune cells and sepsis: a based on Mendelian randomization method study].Semantic proximity Read ↗

Causal association between sepsis and acute respiratory distress syndrome: Evidence from a 2-sample Mendelian randomization study.Semantic proximity Read ↗

A two-step, two-sample Mendelian randomization analysis investigating the interplay between gut microbiota, immune cells, and melanoma skin cancerSemantic proximity Read ↗

A bidirectional mendelian-randomization analyses of genetically predicted circulating levels of systemic inflammatory regulators with risk of sepsisSemantic proximity Read ↗

Identification and validation of potential genes for the diagnosis of sepsis by bioinformatics and 2-sample Mendelian randomization studySemantic proximity Read ↗

Causal effects of gut microbiota on sepsis and sepsis-related death: insights from genome-wide Mendelian randomization, single-cell RNA, bulk RNA sequencing, and network pharmacologySemantic proximity Read ↗

Association between inflammatory factors and melanoma: a bidirectional Mendelian randomization study.Semantic proximity Read ↗

Exploration of the causal relationship between obesity and sepsis and investigation of the mechanism of anoikis in sepsisSemantic proximity Read ↗

Integration of Mendelian Randomization to Explore the Genetic Influences of Pediatric Sepsis: A Focus on RGL4, ATP9A, MAP3K7CL, and DDX11L2Semantic proximity Read ↗

Identifying potential macrophage polarization-related causal genes in sepsis through multi-omics mendelian randomization analysis and experimental validationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.