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Serum SIRT1 Levels and Gene Polymorphisms in Breast Cancer: A Biomarker and Genetic Association Study.

Cell biochemistry and function - 1 Jan 2026

Menambath Desy Thayyil, Adiga Usha, Shetty Vijith, Adiga Sachidananda

Abstract excerpt

Silent mating type information regulation 2 homolog (SIRT1), a key protein involved in cellular regulation, exhibits altered expression in breast cancer. The study aimed to assess serum Sirtuin 1 level, investigate SIRT1 gene polymorphisms, and examine their association with breast cancer. One hundred seventy-two breast cancer patients and 78 healthy age-matched females were included in the study. Genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41572512
DOI: 10.1002/cbf.70170

Genes

SIRT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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