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Article

Bone Phenotype in Autosomal Dominant Polycystic Kidney Disease.

Calcified tissue international - 23 Jan 2026

Jankowska Magdalena, Magnusson Per, Debowska Malgorzata, Lindholm Bengt, Qureshi Abdul Rashid, Lukaszuk Tomasz, Dębska-Ślizień Alicja, Fuster Daniel Guido, Stenvinkel Peter, Haarhaus Mathias

Abstract excerpt

Autosomal dominant polycystic kidney disease (ADPKD) is a systemic ciliary disorder, yet the impact on bone health remains insufficiently defined. Given the expression of polycystins in osteocytes, osteoclasts and extracellular matrix, a disease-specific bone phenotype has been hypothesized. This study aimed to comprehensively characterize the bone phenotype in ADPKD across stages of chronic kidney disease (CKD)...

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Identifiers

PMID: 41571881
DOI: 10.1007/s00223-025-01471-w
PMCID: PMC12827306

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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