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Article

Feasibility of tumor-informed circulating tumor DNA for detecting minimal residual disease in surgically resected biliary tract cancer.

PloS one - 1 Jan 2026

Park Younghee, Kim Kyung Su, Jo Hyunji, Kim Hwang-Phil, Kyung Dong Soo, Yoo Youngeun, Min Seog Ki, Nam Eun Mi, Kim Kyubo

Abstract excerpt

BACKGROUND: We prospectively investigated the potential of tumor-informed circulating tumor DNA (ctDNA) for detecting minimal residual disease (MRD) in surgically resected biliary tract cancer (BTC). METHODS: Personalized panels were developed using individual variants identified from the whole-exome sequencing of surgical specimens from each patient. Two sequential blood samples, collected preoperatively and...

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Identifiers

PMID: 41563984
DOI: 10.1371/journal.pone.0341432
PMCID: PMC12822969

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BTC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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