Article
Tumor-Informed Approach Improved ctDNA Detection Rate in Resected Pancreatic Cancer.
International journal of molecular sciences - 29 Sept 2022
Watanabe Kazunori, Nakamura Toru, Kimura Yasutoshi, Motoya Masayo, Kojima Shigeyuki, Kuraya Tomotaka, Murakami Takeshi, Kaneko Tsukasa, Shinohara Yoshihito, Kitayama Yosuke, Fukuda Keito, Hatanaka Kanako C, Mitsuhashi Tomoko, Pittella-Silva Fabio, Yamaguchi Toshikazu, Hirano Satoshi, Nakamura Yusuke, Low Siew-Kee
Abstract excerpt
Pancreatic cancer is one of the cancers with very poor prognosis; there is an urgent need to identify novel biomarkers to improve its clinical outcomes. Circulating tumor DNA (ctDNA) from liquid biopsy has arisen as a promising biomarker for cancer detection and surveillance. However, it is known that the ctDNA detection rate in resected pancreatic cancer is low compared with other types of cancer. In this study,...
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