Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Real-World Implementation of Next-Generation Sequencing in Sarcoma: Molecular Insights and Therapeutic Outcomes.

Medical sciences (Basel, Switzerland) - 17 Jan 2026

Diab Tasnim, Tarhini Ali, Jaber Ghina, Raffoul Chris, Zeineddine Nijad, Kreidieh Lara, Hemade Ali, Barake Mounir, Saghieh Said, Mahfouz Rami, Assi Hazem I

Abstract excerpt

Background: Sarcomas are rare, aggressive malignancies with limited therapeutic options in advanced stages. This is the first real-world study in the MENA region evaluating the clinical utility of Next-Generation Sequencing (NGS) in guiding sarcoma treatment and improving outcomes. Methods: We retrospectively reviewed sarcoma patients who underwent NGS at a major referral center (2021-2024), comparing clinical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to High-Throughput Nucleotide Sequencing
Share to Adolescent

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to EWSR1 gene

Share to Mutation

Share to Sarcoma

Share to Treatment Outcome

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 41562936
DOI: 10.3390/medsci14010046
PMCID: PMC12821713

Genes

CDK4
CDKN2A
EWSR1
MDM2
RB1
SS18
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Real-World Implementation of Next-Generation Sequencing in Sarcoma: Molecular Insights and Therapeutic Outcomes.PMID 41562936Read ↗

The clinical utility of next-generation sequencing for bone and soft tissue sarcoma.Semantic proximity Read ↗

Genomic Profiling of Sarcomas: A Promising Weapon in the Therapeutic ArsenalSemantic proximity Read ↗

The Role of Next-Generation Sequencing in Sarcomas: Evolution From Light Microscope to Molecular Microscope.Semantic proximity Read ↗

Molecular profiling of soft tissue sarcomas using next-generation sequencing: a pilot study toward precision therapeutics.Semantic proximity Read ↗

Next-generation sequencing for the management of sarcomas with no known driver mutations.Semantic proximity Read ↗

Implementing precision oncology for sarcoma patients: the CCCLMUmolecular tumor board experience.Semantic proximity Read ↗

Molecular Characterization of Soft Tissue Sarcomas Using RNA-Based Next-Generation Sequencing.Semantic proximity Read ↗

A novel next generation sequencing approach to improve sarcoma diagnosisSemantic proximity Read ↗

Introduction and impact of routine whole genome sequencing in the diagnosis and management of sarcoma.Semantic proximity Read ↗

Next-Generation Sequencing for Patients with Sarcoma: A Single Center ExperienceSemantic proximity Read ↗

Molecular profiling of advanced soft-tissue sarcomas: the MULTISARC randomized trialSemantic proximity Read ↗

Precision Oncology in Sarcomas: Divide and ConquerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.