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Article

Implementing precision oncology for sarcoma patients: the CCCLMUmolecular tumor board experience.

Journal of cancer research and clinical oncology - 1 Nov 2023

Berclaz Luc M, Burkhard-Meier Anton, Lange Philipp, Di Gioia Dorit, Schmidt Michael, Knösel Thomas, Klauschen Frederick, von Bergwelt-Baildon Michael, Heinemann Volker, Greif Philipp A, Westphalen C Benedikt, Heinrich Kathrin, Lindner Lars H

Abstract excerpt

PURPOSE: Due to poor outcomes and limited treatment options, patients with advanced bone and soft tissue sarcomas (BS/STS) may undergo comprehensive molecular profiling of tumor samples to identify possible therapeutic targets. The aim of this study was to determine the impact of routine molecular profiling in the setting of a dedicated precision oncology program in patients with BS/STS in a German large-volume...

Topics

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Adolescent
Aged, 80 and over
Biomarkers, Tumor
High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Targeted Therapy

Precision Medicine

Source

Open in PubMed Open full text

Identifiers

PMID: 37542550
DOI: 10.1007/s00432-023-05179-y
PMCID: PMC10590320

Genes

STS
MDM2
PIK3CA
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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