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Article

Immunopathogenic role of the HLA-B∗51:01-specific immunopeptidome in Behçet's disease.

Journal of autoimmunity - 1 Mar 2026

Lee Yeji, Cho Kyung-Cho, Cho Byoung-Kyu, Kim So Hyun, Park Jun Won, Shin Dongjin, Kim Jong-Il, Kang Insoo, Yi Eugene C, Lee Eun Bong

Abstract excerpt

OBJECTIVE: The immunopeptidome, the collection of peptides bound to human leukocyte antigens (HLAs), plays a key role in initiating immune responses. HLA-B∗51:01 is an allele associated with Behçet's disease (BD). However, the role of the immunopeptidome bound to HLA-B∗51:01 in the pathogenesis of BD remains unclear. METHODS: We profiled the HLA-bound immunopeptidome using plasma samples from HLA-B∗51:01-positive...

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Identifiers

PMID: 41558215
DOI: 10.1016/j.jaut.2026.103523

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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