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Article

Rasd2 Knockout Exaggerates the Hearing Loss Phenotype of Tsc1-Deficient Mice.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 31 Jan 2026

Ren Rui, Xing Haiyue, Wang Xiaoying, Du Haibo, Sun Xiaoyang, Xu Zhigang, Wang Yanfei

Abstract excerpt

Rasd2 was originally identified as a striatum-enriched transcript and has been suggested to regulate several signaling pathways including the mTOR pathway. Transcriptomic analyses revealed that Rasd2 is also enriched in inner ear hair cells, while its function in the inner ear remains elusive. Here we showed that RASD2 is localized in the stereocilia as well as the cytoplasm of the hair cells. To investigate its...

Read the complete abstract on PubMed

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Share to Hair Cells, Auditory, Inner
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to TOR Serine-Threonine Kinases

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Source

Identifiers

PMID: 41537759
DOI: 10.1096/fj.202501361R

Genes

RASD2
TSC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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