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Article

Mutational landscape of lung adenocarcinoma in Czechia.

Cancer treatment and research communications - 1 Jan 2026

Ambrozkiewicz Filip, Ali Esraa, Bradova Martina, Slavík Petr, Martinek Petr, Svaton Martin, Hemminki Akseli, Hemminki Kari

Abstract excerpt

Limited DNA sequencing data on lung cancer (LC) patients are available from Eastern Europe where male smoking is commonest in Europe. As sequence analysis is the prerequisite for targeted therapy we provide such data from Czechia (CZ). Additionally, we present novel sequencing data for adenocarcinoma subtypes. Panel sequencing data on 1218 adenocarcinoma patients were available from a single histology laboratory...

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Identifiers

PMID: 41529505
DOI: 10.1016/j.ctarc.2026.101095

Genes

EGFR
KRAS
PIK3CA
TP53
BRAF
MET

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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