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The lncRNA SENCR of polymorphism rs12420823 drives breast cancer progression and its overexpression regulates this process via the miR-3648/FOXD3 axis.

Archives of biochemistry and biophysics - 1 Apr 2026

Kong Lingjun, Xue Jiajie, Yang Jiaqi, Chen Jianxing, Mo Caiqin

Abstract excerpt

The roles of long noncoding RNA SENCR (lncRNA SENCR) and its variant rs12420823 in triple-negative breast cancer (TNBC) susceptibility, progression, and molecular mechanisms remain unclear. thus, this study investigated the association of lncRNA SENCR and rs12420823 with TNBC risk and prognosis and explored the functional SENCR/miR-3648/FOXD3 axis. This study involving 205 TNBC patients and 203 controls, the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Line, Tumor
Share to Cell Proliferation
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Share to Forkhead Transcription Factors
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Source

Identifiers

PMID: 41513216
DOI: 10.1016/j.abb.2026.110732

Genes

FOXD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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