A Proposed TUSC7/miR-211/Nurr1 ceRNET Might Potentially be Disturbed by a cer-SNP rs2615499 in Breast Cancer.

doi:10.1007/s10528-022-10216-5

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A Proposed TUSC7/miR-211/Nurr1 ceRNET Might Potentially be Disturbed by a cer-SNP rs2615499 in Breast Cancer.

Biochemical genetics - 1 Dec 2022

Abdollahzadeh Rasoul, Azarnezhad Asaad, Paknahad Sahereh, Mansoori Yaser, Pirhoushiaran Maryam, Kanaani Khaled, Bafandeh Neda, Jafari Davood, Tavakkoly-Bazzaz Javad

Abstract excerpt

Evidence and in silico analyses showed that TUSC7, miR-211, and Nurr1 may be involved in BC pathogenesis by ceRNET signaling axis. This study aimed to investigate the potential role of TUSC7/miR-211/Nurr1 ceRNET and rs2615499 variant as a novel cer-SNP in BC subjects. The expression assays were conducted by qPCR on tumor tissues (n = 50), tumor-adjacent normal tissues (TANTs) (n = 50), and clinically healthy...

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PMID: 35296964
DOI: 10.1007/s10528-022-10216-5

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