Article
Estimating the Reduction in Genetic Diversity from Background Selection under Non-equilibrium Demography and Partial Selfing.
Molecular biology and evolution - 2 Feb 2026
Mackintosh Alexander, Brault Maxence, Roze Denis, Lascoux Martin, Glémin Sylvain
Abstract excerpt
The effect of natural selection on linked sites has been suggested to be a major determinant of genetic diversity. While it is in principle possible to estimate this effect from genome sequence data, interactions between selection, demography and inbreeding are expected to make inference less reliable. Here, we investigate whether the genome-wide reduction in diversity due to background selection (B¯) can be...
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