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Article

Clinical utility of investigations in triple-negative thrombocytosis: A real-world, multicentre evaluation of UK practice.

British journal of haematology - 1 Oct 2024

Godfrey Anna L, Sousos Nikolaos, Frewin Rebecca, Prahladan Mahesh, Green Anna C, McGregor Andrew, Khan Alesia, Milne Kate, Amin Faisal, Torre Elena, Gudgin Emma J, Lambert Jonathan, Wilson Andrew J, Royston Daniel, Harrison Claire N, Mead Adam J

Abstract excerpt

Diagnosis of essential thrombocythaemia (ET) is challenging in patients lacking JAK2/CALR/MPL mutations. In a retrospective evaluation of 320 patients with 'triple-negative thrombocytosis', we assessed utility of bone marrow histology (90.9% of patients) and myeloid gene panel (MGP, 55.6%). Supportive histology ('myeloproliferative neoplasm-definite/probable', 36.8%) was associated with higher platelet counts and...

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Aged
Aged, 80 and over
Calreticulin
Janus Kinase 2
Receptors, Thrombopoietin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Thrombocythemia, Essential

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PMID: 39004100
DOI: 10.1111/bjh.19643

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