Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Rational Approach to JAK2 Mutation Testing in Patients with Elevated Hemoglobin: Results from the JAK2 Prediction Cohort (JAKPOT) Study.

Journal of general internal medicine - 1 Jun 2023

Chin-Yee Benjamin, Bhai Pratibha, Cheong Ian, Matyashin Maxim, Hsia Cyrus C, Kawata Eri, Ho Jenny M, Levy Michael A, Stuart Alan, Lin Hanxin, Chin-Yee Ian, Kadour Mike, Sadikovic Bekim, Lazo-Langner Alejandro

Abstract excerpt

BACKGROUND: Erythrocytosis, most often measured as an increase in hemoglobin and/or hematocrit, is a common reason for referral to internal medicine and hematology clinics and a rational approach is required to effectively identify patients with polycythemia vera while avoiding over-investigation. AIM: We aimed to develop and validate a simple rule to predict JAK2 mutation positivity based on complete blood count...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to Erythropoietin and Anemia Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hemoglobins

Share to Janus Kinase 2

Share to Mutation

Share to Myeloproliferative Neoplasms: Diagnosis and Treatment

Share to Polycythemia

Share to Polycythemia Vera

Source

Open in PubMed Open full text

Identifiers

PMID: 36451015
DOI: 10.1007/s11606-022-07963-x
PMCID: PMC10271984

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Rational Approach to JAK2 Mutation Testing in Patients with Elevated Hemoglobin: Results from the JAK2 Prediction Cohort (JAKPOT) Study.PMID 36451015Read ↗

Machine Learning Classifier Using Blood Count Parameters and Erythropoietin to Predict JAK2 Mutations in Patients With Erythrocytosis.Semantic proximity Read ↗

TRAKJAK: a complete blood count-based prediction of polycythemia vera at initial erythrocytosis workup to reduce financial and ecological costs.Semantic proximity Read ↗

[Diagnostic work-up of erythrocytosis].Semantic proximity Read ↗

Detection of JAK2 V617F as a first intention diagnostic test for erythrocytosisSemantic proximity Read ↗

Evaluation of "increased" hemoglobin in the JAK2 mutations era: a diagnostic algorithm based on genetic tests.Semantic proximity Read ↗

Low neutrophil-to-lymphocyte ratio identifies secondary polycythemia in patients with erythrocytosis.Semantic proximity Read ↗

Diagnostic Performance of Erythropoietin Levels in Polycythemia Vera: Experience at a Comprehensive Cancer Center.Semantic proximity Read ↗

Mutational Landscape of Patients Referred for Elevated Hemoglobin Level.Semantic proximity Read ↗

Potential limitations of diagnostic standard codes to distinguish polycythemia vera and secondary erythrocytosis: A retrospective case seriesSemantic proximity Read ↗

Evaluation of beta-2 microglobulin, erythropoietin and tobacco use in polycythemic cases.Semantic proximity Read ↗

Prevalance of JAK2 V617F and exon 12 mutations in polycythaemia veraSemantic proximity Read ↗

JAK2-V617F mutation among blood donors: A meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.