Article
The DinG exonuclease acts as a primary quality controller to remove unprocessed ribosomal RNAs.
Nucleic acids research - 5 Jan 2026
Vaitkevičius Karolis, Johansson Jörgen
Abstract excerpt
Bacteria lacking DEAD-box RNA-helicases often show reduced growth and aberrant maturation of ribosomal subunits resulting in fewer active ribosomes. Here, we show that the slow growth observed in a strain lacking the RNA-helicase CshC in the bacterial pathogen Listeria monocytogenes can be suppressed by mutations in the exonuclease DinG. A strain lacking both CshC and DinG increased the number of mature and...
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