Article
Conserved bacterial RNase YbeY plays key roles in 70S ribosome quality control and 16S rRNA maturation.
Molecular cell - 7 Feb 2013
Jacob Asha Ivy, Köhrer Caroline, Davies Bryan William, RajBhandary Uttam Lal, Walker Graham Charles
Abstract excerpt
Quality control of ribosomes is critical for cellular function since protein mistranslation leads to severe physiological consequences. We report evidence of a previously unrecognized ribosome quality control system in bacteria that operates at the level of 70S to remove defective ribosomes. YbeY, a previously unidentified endoribonuclease, and the exonuclease RNase R act together by a process mediated...
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