Article
The highly conserved bacterial RNase YbeY is essential in Vibrio cholerae, playing a critical role in virulence, stress regulation, and RNA processing.
PLoS pathogens - 1 Jun 2014
Vercruysse Maarten, Köhrer Caroline, Davies Bryan W, Arnold Markus F F, Mekalanos John J, RajBhandary Uttam L, Walker Graham C
Abstract excerpt
YbeY, a highly conserved protein, is an RNase in E. coli and plays key roles in both processing of the critical 3' end of 16 S rRNA and in 70 S ribosome quality control under stress. These central roles account for YbeY's inclusion in the postulated minimal bacterial genome. However, YbeY is not essential in E. coli although loss of ybeY severely sensitizes it to multiple physiological stresses. Here, we show...
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