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Article

Decoding the Mutational Hierarchy of Thyroid Cancer and Associated Signaling Pathways.

Archives of medical research - 1 Jun 2026

Nashier Disha, Manjunath Gowrang Kasaba, Parveen Alisha, Malik Sumira, Mitra Tamoghna, Goswami Chandan, Neerathilingam Muniasamy, Watts Ankit, Kumar Abhishek

Abstract excerpt

BACKGROUND: Thyroid cancer (TC) is the most prevalent endocrine malignancy, and its development is influenced by various genomic abnormalities. Activating mutations in oncogenes such as BRAF and RAS significantly contribute to tumorigenesis. Nevertheless, the overall mutational landscape of TC remains unclear. METHODS: We conducted a systematic analysis of genomic data from 1,629 TC samples across four...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41494277
DOI: 10.1016/j.arcmed.2025.103366

Genes

BRAF
TERT
HRAS
NRAS
RET
TG
TP53
TTN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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