Article
Integrating plasma protein-centric multi-omics to evaluate the causal effect of glycosylation on the risk of cancer.
Glycoconjugate journal - 6 Jan 2026
Geng Zhi, Qi Kangwei, Yu Long, Ruan Yuanyuan, Gu Jianxin, Song Shushu
Abstract excerpt
Glycosylation is a crucial post-translational modification, and numerous studies have reported its significant role in cancer progression. Nevertheless, no study has comprehensively analyzed the causal effect of glycosylation on the risk of cancer till now. Herein, we identified 32 SNPs of glycosylation-related genes (GRGs) that correlated with the risk of 8 kinds of cancer by summary-statistics-based mendelian...
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