Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characteristic bone marrow findings in patients with UBA1 somatic mutations and VEXAS syndrome.

Seminars in hematology - 1 Oct 2021

Patel Nisha, Dulau-Florea Alina, Calvo Katherine R

Abstract excerpt

VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) is a newly characterized syndrome with underlying somatic UBA1 mutations in myeloid cells linking hematologic disease with autoinflammatory rheumatologic disorders. Hematologic abnormalities, particularly peripheral blood cytopenia(s) may prompt bone marrow evaluation in patients with known or unrecognized VEXAS syndrome. This review highlights key...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Marrow
Share to Multiple Myeloma
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Myelodysplastic Syndromes

Share to Ubiquitin-Activating Enzymes

Source

Identifiers

PMID: 34802541
DOI: 10.1053/j.seminhematol.2021.10.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characteristic bone marrow findings in patients with UBA1 somatic mutations and VEXAS syndrome.PMID 34802541Read ↗

Benign and malignant hematologic manifestations in patients with VEXAS syndrome due to somatic mutations in UBA1.Semantic proximity Read ↗

A clinical, histopathological, and molecular study of two cases of VEXAS syndrome without a definitive myeloid neoplasm.Semantic proximity Read ↗

Comprehensive morphologic characterization of bone marrow biopsy findings in a large cohort of patients with VEXAS syndrome: A single-institution longitudinal study of 111 bone marrow samples from 52 patients.Semantic proximity Read ↗

VEXAS syndrome: Clinical, hematologic features and a practical approach to diagnosis and management.Semantic proximity Read ↗

How I diagnose and manage VEXAS syndrome.Semantic proximity Read ↗

An update on VEXAS syndrome.Semantic proximity Read ↗

VEXAS within the spectrum of rheumatologic disease.Semantic proximity Read ↗

Morphologic Deciphering of Hematopoietic Cell Vacuolization: Lessons From VEXAS Syndrome and Other Etiologies.Semantic proximity Read ↗

American College of Rheumatology Guidance Statement for Diagnosis and Management of VEXAS Developed by the International VEXAS Working Group Expert Panel.Semantic proximity Read ↗

VEXAS syndrome: Clinical manifestations, diagnosis, and treatment.Semantic proximity Read ↗

Case report of a patient with VEXAS syndrome.Semantic proximity Read ↗

VEXAS syndrome: a new paradigm for adult-onset monogenic autoinflammatory diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.