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The whole genome sequencing offers insights into the susceptibility to the foot-and-mouth disease virus carrier state.

Veterinary research - 3 Jan 2026

Zhang Zhihui, Teng Zhidong, Yin Shuanghui, Mu Suyu, Wei Sumin, Ding Yaozhong, Zhang Yun, Wang Shuang, Li Yijing, Sun Shiqi, Guo Huichen

Abstract excerpt

Foot-and-mouth disease virus (FMDV) establishes persistent infection in more than 50% of infected ruminants, irrespective of vaccination status, implicating potential contributions of host genetic variations to viral persistence. In this study, we conducted whole-genome resequencing of a cohort of 22 cattle, comprising 7 carriers and 15 noncarriers. Clean reads were mapped to the cattle (Bos taurus) reference...

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Identifiers

PMID: 41484999
DOI: 10.1186/s13567-025-01697-4
PMCID: PMC12866560

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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