Article
Evolution of foot-and-mouth disease virus intra-sample sequence diversity during serial transmission in bovine hosts.
Veterinary research - 1 Mar 2013
Morelli Marco J, Wright Caroline F, Knowles Nick J, Juleff Nicholas, Paton David J, King Donald P, Haydon Daniel T
Abstract excerpt
RNA virus populations within samples are highly heterogeneous, containing a large number of minority sequence variants which can potentially be transmitted to other susceptible hosts. Consequently, consensus genome sequences provide an incomplete picture of the within- and between-host viral evolutionary dynamics during transmission. Foot-and-mouth disease virus (FMDV) is an RNA virus that can spread from primary...
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