Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Cell Painting PLUS Method: Phenotypic Profiling Using Iterative Staining-Elution Cycles.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2026

von Coburg Elena, Dunst Sebastian

Abstract excerpt

Cell Painting (CP) is a widely used imaging-based method for untargeted high-throughput phenotypic profiling (HTPP) of compounds or genetic perturbations that lead to morphological changes in cells. Here, we describe the Cell Painting PLUS (CPP) method, an efficient, robust, and broadly applicable HTPP approach that overcomes certain boundaries of the standard CP method. In CPP, an elution buffer enables...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fluorescent Dyes
Share to CP gene
Share to High-Throughput Screening Assays

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Image Processing, Computer-Assisted

Share to Microscopy, Fluorescence

Share to Phenotype

Share to Software

Share to Staining and Labeling

Source

Identifiers

PMID: 41479046
DOI: 10.1007/978-1-0716-4985-5_2

Genes

CP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Cell Painting PLUS Method: Phenotypic Profiling Using Iterative Staining-Elution Cycles.PMID 41479046Read ↗

Cell Painting PLUS: An Iterative Staining-Elution Protocol for High-Content Phenotypic Screenings.Semantic proximity Read ↗

Optimizing the Cell Painting assay for image-based profilingSemantic proximity Read ↗

Cell Painting, an image-based assay for morphological profilingSemantic proximity Read ↗

Time resolved cell painting enables rapid assessment of cell phenotypes.Semantic proximity Read ↗

Assessing the performance of the Cell Painting assay across different imaging systemsSemantic proximity Read ↗

SPACe: an open-source, single-cell analysis of Cell Painting data.Semantic proximity Read ↗

Predicting cell health phenotypes using image-based morphology profiling.Semantic proximity Read ↗

JUMP Cell Painting dataset: morphological impact of 136,000 chemical and genetic perturbationsSemantic proximity Read ↗

Compound Functional Prediction Using Multiple Unrelated Morphological Profiling Assays.Semantic proximity Read ↗

High-resolution phenotypic profiling of natural products-induced effects on the single-cell level.Semantic proximity Read ↗

High throughput microscopy and single cell phenotypic image-based analysis in toxicology and drug discovery.Semantic proximity Read ↗

Morphology and gene expression profiling provide complementary information for mapping cell state.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.