Impact of CD34 + Bone Marrow Cell Heterogeneity and HMOX1 Promoter Polymorphism on Neutrophil Engraftment in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation.

Abstract excerpt

Hematopoietic stem cell transplantation (HSCT) is a therapeutic option for various pediatric diseases. In this study, we analyzed 52 pediatric patients undergoing allogeneic HSCT to determine how the content of myeloid and lymphoid CD34+ progenitor cells, as well as HMOX1 promoter polymorphisms, affects neutrophil (NE) and platelet engraftment (PE). We found that NE was significantly accelerated in patients who...

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