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The hallmarks of hematopoietic stem cell transplantation for pediatric acute myeloid leukemia

9 Jul 2025

Abstract excerpt

Allogeneic hematopoietic stem cell transplantation (HSCT) has significantly improved the outcome of children with high-risk (HR) acute myeloid leukemia (AML). Implementing allogeneic HSCT depends on numerous factors, including adverse cytogenetics, molecular abnormalities, poor response to first-line treatment, or relapsed or primary refractory disease. In HR AML, allogeneic HSCT is considered to be the...

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PMID: 40634512
DOI: 10.1038/s41375-025-02685-5

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