Article
Geographic and Population Distributions of Human Immunodeficiency Virus (HIV)-1 and HIV-2 Circulating Subtypes: A Systematic Literature Review and Meta-analysis (2010-2021).
The Journal of infectious diseases - 28 Nov 2023
Williams Alexandria, Menon Sonia, Crowe Madeleine, Agarwal Neha, Biccler Jorne, Bbosa Nicholas, Ssemwanga Deogratius, Adungo Ferdinard, Moecklinghoff Christiane, Macartney Malcolm, Oriol-Mathieu Valerie
Abstract excerpt
BACKGROUND: HIV poses significant challenges for vaccine development due to its high genetic mutation and recombination rates. Understanding the distribution of HIV subtypes (clades) across regions and populations is crucial. In this study, a systematic review of the past decade was conducted to characterize HIV-1/HIV-2 subtypes. METHODS: A comprehensive search was performed in PubMed, EMBASE, and CABI Global...
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