Article
Complete genomes of Rickettsia typhi reveal a clonal population.
PLoS neglected tropical diseases - 1 Dec 2025
Keeratipusana Chantisa, Phuklia Weerawat, Phommadeechack Vanheuang, Thaipadungpanit Janjira, Chansamouth Vilada, Phommasone Koukeo, Rattanavong Sayaphet, Moore Catrin E, Robinson Matthew T, Richards Allen L, Newton Paul N, Batty Elizabeth M
Abstract excerpt
Murine typhus, caused by infection with Rickettsia typhi, is a neglected disease contributing to infectious disease burden in south- and southeast Asia. Despite its importance, we have minimal knowledge of the genomics of R. typhi, with only four complete genomes being sequenced prior to this work. We sequenced a further 25 genomes including historical strains collected before 1976 from both human and rat hosts,...
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