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Article

Multi-omics dissection of the genetic regulation underlying fatty acid composition in cattle.

Genome biology - 22 Dec 2025

Zhang Tianliu, Niu Qunhao, Wang Tianzhen, Wu Jiayuan, Zhu Bo, Wang Zezhao, Gao Xue, Chen Yan, Gao Huijiang, Zhang Lupei, Fu Tong, Gao Tengyun, Liu George E, Li Junya, Xu Lingyang

Abstract excerpt

BACKGROUND: Fatty acid composition is a complex trait governed by a polygenic architecture. Although numerous genetic variants associated with fatty acids have been identified through genome-wide association studies (GWAS), the underlying regulatory mechanisms remain incompletely understood. In this study, we employed a multi-omics approach to deeply dissect the genetic regulation of fatty acids in cattle....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41430323
DOI: 10.1186/s13059-025-03885-z
PMCID: PMC12723948

Genes

SCD
ACAA2

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