Article
SNP co-association and network analyses identify E2F3, KDM5A and BACH2 as key regulators of the bovine milk fatty acid profile.
Scientific reports - 11 Dec 2017
Pegolo Sara, Dadousis Christos, Mach Núria, Ramayo-Caldas Yuliaxis, Mele Marcello, Conte Giuseppe, Schiavon Stefano, Bittante Giovanni, Cecchinato Alessio
Abstract excerpt
The fatty acid (FA) profile has a considerable impact on the nutritional and technological quality of milk and dairy products. The molecular mechanism underlying the regulation of fat metabolism in bovine mammary gland have been not completely elucidated. We conducted genome-wide association studies (GWAS) across 65 milk FAs and fat percentage in 1,152 Brown Swiss cows. In total, we identified 175 significant...
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