Article
Association of HMGB1 and HMGB2 genetic polymorphisms with lung cancer chemotherapy response.
Clinical and experimental pharmacology & physiology - 1 Jun 2014
Wang Ying, Li Xiang-Ping, Yin Ji-Ye, Zhang Yu, He Hui, Qian Chen-Yue, Chen Juan, Zheng Yi, Smieszkol Kamila, Fu Yi-Lan, Chen Zi-Yu, Zhou Hong-Hao, Liu Zhao-Qian
Abstract excerpt
The aim of the present study was to investigate the association of genetic polymorphisms in high mobility group box 1 and 2 (HMGB1 and HMGB2, respectively) with platinum-based chemotherapy responses in Chinese lung cancer patients. In total, 338 Chinese lung cancer patients (154 responders and 184 non-responders) were recruited to the study. All patients received at least two cycles of first-line platinum-based...
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