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Article

Gut microbiota as a causal mediator linking inflammatory cytokines and ageing phenotypes.

Biogerontology - 13 Dec 2025

Liu Qiyu, Li Weidong, Diao Wuliang, Shi Wenjun, Yu Li, Cai Yuchen, Cai Xueyao

Abstract excerpt

Population ageing is a global phenomenon with significant implications for public health. Research has highlighted a relationship between gut microbiota, inflammatory cytokines, and ageing, yet the underlying causal mechanisms remain elusive. This study uses Mendelian randomization (MR) analysis to investigate causal relationships between gut microbiota, inflammatory cytokines, and ageing phenotypes. We leveraged...

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PMID: 41389138
DOI: 10.1007/s10522-025-10369-x

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GCA

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