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Article

Gut microbiota, inflammatory proteins, and allergic diseases: A bidirectional Mendelian randomization study.

Medicine - 21 Aug 2026

Zhu Hao, Dou Minghang, Jin Xiangqun

Abstract excerpt

Some authors suggest a link between gut microbiota and allergic diseases; however, the genetically predicted relationship and the role of inflammatory proteins as mediators are still uncertain. Gut microbiota, inflammatory proteins, and 5 types of allergic diseases, namely allergic rhinitis (AR), atopic dermatitis, allergic conjunctivitis, food allergy, and asthma, were identified from large-scale genome-wide...

Topics

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Gastrointestinal Microbiome
AR gene
Genetic Predisposition to Disease
Genome-Wide Association Study
Hypersensitivity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mendelian Randomization Analysis

Quantitative Trait Loci

Source

Open in PubMed Open full text

Identifiers

PMID: 42629664
DOI: 10.1097/MD.0000000000050266
PMCID: PMC13502868

Genes

AR
CD40
CX3CL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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