4-octyl itaconate modulates virulence-associated phenotypes and oxidative stress resistance in avian pathogenic Escherichia coli by targeting menB and wza.

doi:10.1016/j.psj.2025.106202

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

4-octyl itaconate modulates virulence-associated phenotypes and oxidative stress resistance in avian pathogenic Escherichia coli by targeting menB and wza.

Poultry science - 1 Feb 2026

Che Chuanyan, Fan Xiuqi, Wang Haiyang, Wang Zhihao, Bao Yinli, Jiang Wei, Nawaz Saqib, Yin Huifang, Han Xiangan

Abstract excerpt

Avian Pathogenic Escherichia coli (APEC) causes substantial economic losses to the poultry industry, primarily due to its diverse serotypes and extensive drug resistance. Itaconate, a metabolite of the tricarboxylic acid (TCA) cycle, demonstrates antimicrobial activity. However, the effect of itaconate on the biological characteristics of APEC remains unexplored. Because itaconate itself has poor membrane...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biofilms
Share to Chickens
Share to Escherichia coli Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Escherichia coli Proteins

Share to Oxidative Stress

Share to Poultry Diseases

Share to Succinates

Share to Virulence

Source

Open in PubMed Open full text

Identifiers

PMID: 41386169
DOI: 10.1016/j.psj.2025.106202
PMCID: PMC12756159

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.