DNA methylation models of protein abundance across the lifecourse.

Abstract excerpt

BACKGROUND: Multiple studies have shown that DNA methylation (DNAm) models of protein abundance can be informative about exposure, phenotype and disease risk. Here we investigate and provide descriptive details of the capacity of DNAm to capture non-genetic variation in protein abundance across the lifecourse. METHODS: We evaluated the performance of 14 previously published DNAm models of protein abundance...

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